In his early teens Matt De Florio took accordion lessons and studied relentlessly. However, a visit to New York in the mid 40's changed everything when Matt had the opportunity to meet two accordion greats: Pietro Diero and Charles Magnante. These two players became a great inspiration and soon after Matt decided to begin a professional career in music. Upon returning to Toronto, Matt got a job at the Old Mill Restaurant where he played for the next three years. After leaving the Old Mill, Matt played in the prestigious Imperial Room at The Royal York Hotel for two years. Matt also took great pride in playing at the Horse Shoe Tavern alongside Peter Appleyard: the up and coming jazz vibraphonist.
Matt often performed at CBC radio shows and many private engagements. However, the most memorable experience was the five years he played on the CBC Television show Holiday Ranch with Cliff McKay. A total of over two hundred shows were filmed in front of a live camera between 1953-1957. Matt played many solos and wrote his own arrangements for the group during this time. Holiday Ranch was host to many guest artists, which included singers Robert Goulet, Perry Como and Lorne Greene from the TV show Bonanza. On one occasion at the Canadian National Exhibition, Matt played a solo, after which Bob Hope made a guest appearance. Matt also contributed to the accordion community by giving lessons and writing three books: Studio Method I, Studio Method II, and Fun to Play the Accordion. In 1958, Matt left the spotlight to start his own business in Toronto that was originally called De Florio Imports. This began after meeting with a representative from an accordion factory in Castelfidardo, Italy. Later in the 60's, the business name was changed to Musical Instruments of Canada.